Ventricular arrhythmias and prevention of sudden cardiac death

Alekperov Z. E.

ABSTRACT

This review article presents updated European guidelines for the management of patients with ventricular arrhythmias (VA) and prevention of sudden cardiac death (SCD). New understanding of SCD  epidemiology, modern concepts on genetics, imaging and a large volume of clinical data for stratification of VA and SCD  risk, as well as advances in diagnostic assessment and therapeutic strategies contributed to the revision of the previous recommendations. In the given recommendations the leading role is given to genetic analyses, invasive and noninvasive methods of diagnostics, such as electrophysiological examination, programmed electric stimulation of heart, magnetic resonance imaging (MRI). In terms of preventive treatment, recommendations on expanding general education of the population, the principles of first aid to persons with sudden cardiac arrest and ensuring the availability of out-of-hospital cardiac defibrillation have been prioritized. The indications for beta-blockers, flecainide, implantable cardioverter-defibrillators, catheter ablation, implantable programmed antitachycardia stimulation devices, and left-sided sympathetic cardiac denervation have expanded considerably.

Keywords: prevention, genetic risk factors, ventricular arrhythmias, sudden cardiac arrest, sudden death.

For citation:

Alekperov Z. E. Ventricular arrhythmias and prevention of sudden cardiac death. International Journal of Heart and Vascular Diseases. 2023. 11(38): 43-50. DOI: 10.24412/2311-1623-2022-38-52-61